Composition #1: Baasanjav-Gerber, Chimgee., Hollnagel, Heli Miriam., Brauchmann, Jana., Iori, Renato., Glatt, Hansruedi. Detection of genotoxicants in Brassicales using endogenous DNA as a surrogate target and adducts determined by 32P-postlabelling as an experimental end point. mutagenesis, 2011, vol. 26, no. 3, p. 407–413. .
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Plant part:
Live plants (as part-nature) (A0BA0)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
unspecified
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Substance:
Glucosinolates (RF-00000330-TOX)
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Additional substance description:
Glucobrassicin; 4-methoxy-glucobrassicin and neoglucobrassicin
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Indol glucosinolates (Glucobrassicin; 4-methoxy-glucobrassicin and neoglucobrassicin)
Endpoint study
#1: BARNOUIN, J., CHALUS, T., LESCOURRET, F. INCREASED PERINATAL FRENCH DAIRY CALF MORTALITY ASSOCIATED WITH FRESH RAPE IN THE PREPARTUM DIET . preventive veterinary medicine, 1992, vol. 12, no. 1-2, p. 111–120. DOI: 10.1016/0167-5877(92)90074-P.
[
DOI link]
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Study relevance:
Animal (target species) health
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Plant part:
Live plants (as part-nature) (A0BA0)
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Preparation/Extraction method:
Fresh (A166Y)
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Type of toxicological test:
reproduction toxicity (CHD009TT)
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Tested organism:
Cattle (as animal) (A057E)
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Route of exposure:
ORAL: FEED (OECD2230PL)
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Number of organisms dosed:
79
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
REPRODUCTIVE (TOX05A)
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Target tissue:
Urogenital (TT006A)
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Effect description:
higher difficult calving incidences; perinatal mortality
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Effect or parameter linked to the endpoint:
mortality (CHD010BE)
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Internal remarks:
perinatal mortality
