Composition #1: Bartolome, Arlene P., Villasenor, Irene M., Yang, Wen-Chin. Bidens pilosa L. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology. . evidence-based complementary and alternative medicine : ecam, 2013, vol. 2013, p. 340215. DOI: 10.1155/2013/340215.
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DOI link]
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Plant part:
Live plants (as part-nature) (A0BA0)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
p-coumaric acid (RF-00010717-PAR)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
p-coumaric acid
Composition #2: Bartolome, Arlene P., Villasenor, Irene M., Yang, Wen-Chin. Bidens pilosa L. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology. . evidence-based complementary and alternative medicine : ecam, 2013, vol. 2013, p. 340215. DOI: 10.1155/2013/340215.
[
DOI link]
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
Eugenol (RF-00003807-PAR)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
eugenol
Composition #3: Bartolome, Arlene P., Villasenor, Irene M., Yang, Wen-Chin. Bidens pilosa L. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology. . evidence-based complementary and alternative medicine : ecam, 2013, vol. 2013, p. 340215. DOI: 10.1155/2013/340215.
[
DOI link]
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
Eugenol (RF-00003807-PAR)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
eugenol
Composition #4: Bartolome, Arlene P., Villasenor, Irene M., Yang, Wen-Chin. Bidens pilosa L. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology. . evidence-based complementary and alternative medicine : ecam, 2013, vol. 2013, p. 340215. DOI: 10.1155/2013/340215.
[
DOI link]
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Plant part:
Live plants (as part-nature) (A0BA0)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
gallic acid (RF-00003821-PAR)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Gallic acid
Composition #5: Kone, W.M., Kande, B. Qualitative analysis of the pyrrolizidine alkaloids from 11 asteraceae and boraginaceae used in traditional medicine in cote d'lvoire. research journal of phytochemistry, 2012, vol. 6, no. 3, p. 75–83. DOI: 10.3923/rjphyto.2012.75.83.
[
DOI link]
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Dichlormethan
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Substance:
Pyrrolizidine alkaloids (RF-00000230-TOX)
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Analytical method code:
Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
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Analytical method - additional description:
TLC
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
pyrrolizidine alkaloids
Composition #6: Yang, Wen-Chin. Botanical, Pharmacological, Phytochemical, and Toxicological Aspects of the Antidiabetic Plant Bidens pilosa L. . evidence-based complementary and alternative medicine : ecam, 2014, vol. 2014, p. 698617–698617. DOI: 10.1155/2014/698617.
[
DOI link]
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Plant part:
Live plants (as part-nature) (A0BA0)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Substance:
Polyynes Polyynes (RF-00004322-PAR)
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Polyynes
Composition #7: Arroyo, Jorge., Bonilla, Pablo., Ráez, Ernesto., Suárez, Silvia., Palomino, Robert., Terán, Segundo., Villarreal, Aníbal., Marin, Manuel., Chenguayén, Julio., Justil, Hugo. Compuestos fenólicos de la fracción metanólica de Bidens pilosa, sobre la neoplasia gástrica, inducida en ratas . anales de la facultad de medicina, 2007, vol. 68, no. 2, p. 105–112. .
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Plant part:
Unspecified (A07XD)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
ethanol,methanol,cloroform,n-hexane and water
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Substance:
Tannins (RF-00004337-PAR)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Tannins
Composition #8: Souza, Bruna A., Da Silva, Lidiane C., Chicarino, Evelyn D., Bessa, Elisabeth C. A. Preliminary phytochemical screening and molluscicidal activity of the aqueous extract of Bidens pilosa Linne (Asteraceae) in Subulina octona (Mollusca, Subulinidade). ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS, 2013, vol. 85, no. 4, p. 1557–1566. DOI: 10.1590/0001-37652013111812.
[
DOI link]
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Plant part:
Leaves (as part-nature) (A0EKT)
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Extraction/Preparation method:
Solvent extraction (A0BZR)
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Additional extraction description:
Hydrodistillation
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Substance:
Saponins (RF-00004333-PAR)
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Analytical method code:
Phytochemical screening (F604A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Saponins
Endpoint study
#1: Nikolajsen, Tine., Nielsen, Frank., Rasch, Vibeke., Sorensen, Pernille H., Ismail, Flora., Kristiansen, Uffe., Jager, Anna K. Uterine contraction induced by Tanzanian plants used to induce abortion. journal of ethnopharmacology, 2011, vol. 137, no. 1, p. 921–925. DOI: 10.1016/j.jep.2011.05.026.
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DOI link]
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Study relevance:
Human health
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Preparation/Extraction method:
Solvent extraction (A0BZR)
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Additional plant/substance description:
ethanol extract
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Type of toxicological test:
in vitro (CHD061TT)
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Tested organism:
Rat (as animal) (A0CNV)
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Strain of test organism:
Sprague-Dawley (CHD012ST)
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Endpoint measured:
Dose not reported (CHD066EP)
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Critical effect:
REPRODUCTIVE (TOX05A)
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Target tissue:
urogenital: Uterus (TT052A)
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Effect description:
increase of uterine force of contraction
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Effect or parameter linked to the endpoint:
reproduction (CHD014BE)
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Internal remarks:
increases uterine force of contraction
Genotox #1: Costa, Ronaldo de Jesus., Diniz, Andrea., Mantovani, Mario Sergio., Jordao, Berenice Quinzani. In vitro study of mutagenic potential of Bidens pilosa Linne and Mikania glomerata Sprengel using the comet and micronucleus assays. . journal of ethnopharmacology, 2008, vol. 118, no. 1, p. 86–93. DOI: 10.1016/j.jep.2008.03.014.
[
DOI link]
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Study category:
Genotoxicity
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Type of toxicological test:
single cell gel/comet assay in mammalian cells for detection of DNA damage (CHD040TT)
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Tested organism:
Mammals (as animal) (A056H)
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Endpoint measured:
DNA damage and/or repair
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Remarks on genotox study:
Comet assay
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Internal remarks:
The Comet assay on the infusion of aerial part indicated genotoxic effects
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Internal ID:
MEDLINE:18485638