EFSA Compendium of Botanicals

Draft - work in progress

Bergenia crassifolia (L.) Fritsch

Family:: Saxifragaceae
Approval state:: Approved
Number of articles retrieved:: 210
Number of processed references:: 4

Compositions

#1: Tannins #2: lectins #3: Tannins #4: Benzaldehyde #5: ellagitannins (hydrolysable tannins) #6: 1,2,6-tri-O-galloyl glucose (Gallic acid derivative) #7: Digalloylglucose (Hydrolysable tannin) #8: 1-O-galloylglucose (Gallic acid derivative) #9: Tetragalloylglucose (hydrolysable tannin)

Endpoint Studies

Genotoxicity

Composition #1: Makkar, H. P. S., Norvsambuu, T., Lkhagvatseren, S., Becker, K. Plant Secondary Metabolites in some Medicinal Plants of Mongolia Used for Enhancing Animal Health and Production. Tropicultura, 2009, vol. 27, no. 3, p. 159–167. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Aqueous acetone,
Substance:

Tannins (RF-00004337-PAR)
Analytical method code:

Unspecified (F598A)
Result unit:

Gram/kilogram (G015A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

169.8-204.7
Internal remarks:

Tannins

Composition #2: Makkar, H. P. S., Norvsambuu, T., Lkhagvatseren, S., Becker, K. Plant Secondary Metabolites in some Medicinal Plants of Mongolia Used for Enhancing Animal Health and Production. Tropicultura, 2009, vol. 27, no. 3, p. 159–167. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

aqueous acetone
Substance:

Lectins (RF-00000439-ORG)
Analytical method code:

Unspecified (F598A)
Result unit:

Gram/kilogram (G015A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

10.25
Internal remarks:

lectins

Composition #3: Spiridonov, Nikolay A., Konovalov, Dmitrii A., Arkhipov, Vladimir V. Cytotoxicity of some russian ethnomedicinal plants and plant compounds. phytotherapy research, 2005, p. 428–432. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Tannins (RF-00004337-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins

Composition #4: Zhao, JY., Liu, JM., Zhang, XY., Liu, ZJ., Tsering, T., Zhong, Y., Nan, P. Chemical composition of the volatiles of three wild Bergenia species from western China . flavour and fragrance journal, 2006, vol. 21, no. 3, p. 431–434. DOI: 10.1002/ffj.1689. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Additional extraction description:

steam distillation
Substance:

Benzaldehyde (RF-00008323-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.13
Internal remarks:

Benzaldehyde

Composition #5: Salminen, Juha-Pekka., Shikov, Alexander N., Karonen, Maarit., Pozharitskaya, Olga N., Kim, Jorma., Makarov, Valery G., Hiltunen, Raimo., Galambosi, Bertalan. Rapid profiling of phenolic compounds of green and fermented Bergenia crassifolia L. leaves by UPLC-DAD-QqQ-MS and HPLC-DAD-ESI-QTOF-MS. NATURAL PRODUCT RESEARCH, 2014, vol. 28, no. 19, p. 1530–1533. DOI: 10.1080/14786419.2014.923999. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Ellagitannins (hydrolysable tannins) Ellagitannins (hydrolysable tannins) (RF-00004379-PAR)
Analytical method code:

HPLC-DAD (F587A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

18.06
Internal remarks:

ellagitannins (hydrolysable tannins)

Composition #6: Salminen, Juha-Pekka., Shikov, Alexander N., Karonen, Maarit., Pozharitskaya, Olga N., Kim, Jorma., Makarov, Valery G., Hiltunen, Raimo., Galambosi, Bertalan. Rapid profiling of phenolic compounds of green and fermented Bergenia crassifolia L. leaves by UPLC-DAD-QqQ-MS and HPLC-DAD-ESI-QTOF-MS. NATURAL PRODUCT RESEARCH, 2014, vol. 28, no. 19, p. 1530–1533. DOI: 10.1080/14786419.2014.923999. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Tannins (RF-00004337-PAR)
Additional substance description:

1,2,6-Trigalloylglucose
Analytical method code:

HPLC-DAD (F587A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.73
Internal remarks:

1,2,6-tri-O-galloyl glucose (Gallic acid derivative)

Composition #7: Salminen, Juha-Pekka., Shikov, Alexander N., Karonen, Maarit., Pozharitskaya, Olga N., Kim, Jorma., Makarov, Valery G., Hiltunen, Raimo., Galambosi, Bertalan. Rapid profiling of phenolic compounds of green and fermented Bergenia crassifolia L. leaves by UPLC-DAD-QqQ-MS and HPLC-DAD-ESI-QTOF-MS. NATURAL PRODUCT RESEARCH, 2014, vol. 28, no. 19, p. 1530–1533. DOI: 10.1080/14786419.2014.923999. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Digalloylglucose (RF-00011365-PAR)
Analytical method code:

HPLC-DAD (F587A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.6
Internal remarks:

Digalloylglucose (Hydrolysable tannin)

Composition #8: Salminen, Juha-Pekka., Shikov, Alexander N., Karonen, Maarit., Pozharitskaya, Olga N., Kim, Jorma., Makarov, Valery G., Hiltunen, Raimo., Galambosi, Bertalan. Rapid profiling of phenolic compounds of green and fermented Bergenia crassifolia L. leaves by UPLC-DAD-QqQ-MS and HPLC-DAD-ESI-QTOF-MS. NATURAL PRODUCT RESEARCH, 2014, vol. 28, no. 19, p. 1530–1533. DOI: 10.1080/14786419.2014.923999. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Tannins (RF-00004337-PAR)
Additional substance description:

1-O-Galloylglucose
Analytical method code:

HPLC-DAD (F587A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.98
Internal remarks:

1-O-galloylglucose (Gallic acid derivative)

Composition #9: Salminen, Juha-Pekka., Shikov, Alexander N., Karonen, Maarit., Pozharitskaya, Olga N., Kim, Jorma., Makarov, Valery G., Hiltunen, Raimo., Galambosi, Bertalan. Rapid profiling of phenolic compounds of green and fermented Bergenia crassifolia L. leaves by UPLC-DAD-QqQ-MS and HPLC-DAD-ESI-QTOF-MS. NATURAL PRODUCT RESEARCH, 2014, vol. 28, no. 19, p. 1530–1533. DOI: 10.1080/14786419.2014.923999. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

Tannins (RF-00004337-PAR)
Additional substance description:

1,2,3,6-Tetragalloylglucose
Analytical method code:

HPLC-DAD (F587A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.93
Internal remarks:

Tetragalloylglucose (hydrolysable tannin)