EFSA Compendium of Botanicals

Draft - work in progress

Wax gourd (as plant) // Benincasa hispida (Thunb.) Cogn.

Family:: Cucurbitaceae
Approval state:: Approved
Number of articles retrieved:: 789
Number of processed references:: 5

Compositions

#1: Saponins in seed #2: alkaloids in seed #3: cucurbitacins in seed #4: Alkaloids in dried leaves methanolic exract #5: Tannins in dried leaves methanolic extracts #6: Saponins in dried leaves methanolic extract #7: Tannins in dry leaves petroleum ether extract #8: Saponins #9: Coumarins #10: Cardiac gycosides #11: alkaloids #12: tannins #13: Gallic acid

Endpoint Studies

Genotoxicity

Composition #1: Pagare, M.S., Patil, L., Kadam, V.J. Benincasa hispida: A natural medicine. research journal of pharmacy and technology, 2011, vol. 4, no. 12, p. 1941–1944. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Saponins (RF-00004333-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins in seed

Composition #2: Pagare, M.S., Patil, L., Kadam, V.J. Benincasa hispida: A natural medicine. research journal of pharmacy and technology, 2011, vol. 4, no. 12, p. 1941–1944. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

Alkaloids (RF-00004360-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alkaloids in seed

Composition #3: Pagare, M.S., Patil, L., Kadam, V.J. Benincasa hispida: A natural medicine. research journal of pharmacy and technology, 2011, vol. 4, no. 12, p. 1941–1944. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Substance:

cucurbitacins (RF-00004352-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

cucurbitacins in seed

Composition #4: Momin, M.A.M., Rashid, M.M., Urmi, K.F., Rana, M.S. Phytochemical screening and investigation of antioxidant and cytotoxicity potential of different extracts of selected medicinal plants of Bangladesh. research journal of pharmacy and technology, 2013, vol. 6, no. 9, p. 1042–1050. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

95% methanol
Substance:

Alkaloids (RF-00004360-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Alkaloids in dried leaves methanolic exract

Composition #5: Momin, M.A.M., Rashid, M.M., Urmi, K.F., Rana, M.S. Phytochemical screening and investigation of antioxidant and cytotoxicity potential of different extracts of selected medicinal plants of Bangladesh. research journal of pharmacy and technology, 2013, vol. 6, no. 9, p. 1042–1050. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

95% methanol
Substance:

Tannins (RF-00004337-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins in dried leaves methanolic extracts

Composition #6: Momin, M.A.M., Rashid, M.M., Urmi, K.F., Rana, M.S. Phytochemical screening and investigation of antioxidant and cytotoxicity potential of different extracts of selected medicinal plants of Bangladesh. research journal of pharmacy and technology, 2013, vol. 6, no. 9, p. 1042–1050. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

95% methanol
Substance:

Saponins (RF-00004333-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins in dried leaves methanolic extract

Composition #7: Momin, M.A.M., Rashid, M.M., Urmi, K.F., Rana, M.S. Phytochemical screening and investigation of antioxidant and cytotoxicity potential of different extracts of selected medicinal plants of Bangladesh. research journal of pharmacy and technology, 2013, vol. 6, no. 9, p. 1042–1050. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether
Substance:

Tannins (RF-00004337-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Tannins in dry leaves petroleum ether extract

Composition #8: Nadhiya, K., Haripriya, D., Vijayalakshmi, K. Pharmacognostic and preliminary phytochemical analysis on Benincasa hispida fruit. asian journal of pharmaceutical and clinical research, 2014, vol. 7, no. 1, p. 98–101. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol and/or water
Substance:

Saponins (RF-00004333-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins

Composition #9: Nadhiya, K., Haripriya, D., Vijayalakshmi, K. Pharmacognostic and preliminary phytochemical analysis on Benincasa hispida fruit. asian journal of pharmaceutical and clinical research, 2014, vol. 7, no. 1, p. 98–101. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol and/or water
Substance:

coumarins (RF-00004351-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Coumarins

Composition #10: Nadhiya, K., Haripriya, D., Vijayalakshmi, K. Pharmacognostic and preliminary phytochemical analysis on Benincasa hispida fruit. asian journal of pharmaceutical and clinical research, 2014, vol. 7, no. 1, p. 98–101. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Ethanol and/or water
Substance:

cardiac glycosides (RF-00010823-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Cardiac gycosides

Composition #11: Une, H.D., Doshi, G.M. Chromatographic studies on Benincasa hispida (thunb.) Cogn. Seed extract scrutinized by HPLC and HPTLC. pharmacognosy journal, 2014, vol. 6, no. 3, p. 42–48. DOI: 10.5530/pj.2014.3.7. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Petroleum ether
Substance:

Alkaloids (RF-00004360-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

alkaloids

Composition #12: Une, H.D., Doshi, G.M. Chromatographic studies on Benincasa hispida (thunb.) Cogn. Seed extract scrutinized by HPLC and HPTLC. pharmacognosy journal, 2014, vol. 6, no. 3, p. 42–48. DOI: 10.5530/pj.2014.3.7. [DOI link]

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Petroleyum ether
Substance:

Tannins (RF-00004337-PAR)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

tannins

Composition #13: Fatariah, Z., Zulkhairuazha, T. Y. Tg., Rosli, W. I. Wan. Quantitative HPLC Analysis of Gallic Acid in Benincasa hispida Prepared with Different Extraction Techniques. SAINS MALAYSIANA, 2014, vol. 43, no. 8, p. 1181–1187. .

Language:

English (en)
Plant part:

Fruit unspecified (as part-nature) (A067D)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water- drying and heating
Substance:

gallic acid (RF-00003821-PAR)
Result unit:

Milligram/kilogram (G061A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.7
Internal remarks:

Gallic acid