EFSA Compendium of Botanicals

Draft - work in progress

Bauhinia variegata L.

Family:: Fabaceae
Approval state:: Approved
Number of articles retrieved:: 540
Number of processed references:: 5

Compositions

#1: .Alkaloids #2: Glycosides Cardiac #3: Saponins #4: oxalates #5: Trypsin inhibitor #6: tannins #7: myrcene #8: Camphor

Endpoint Studies

#1: hematological changes at high doses

Genotoxicity

Composition #1: Gupta, Rajesh., Paarakh, Padmaa M., Gavani, Usha. Pharmacognostical and phytochemical screening of Bauhinia variegata Linn leaves.. Journal of Pharmacy Research, 2009, vol. 2, no. 7, p. 1196–1198. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol
Substance:

Alkaloids (RF-00004360-PAR)
Analytical method - additional description:

qualitative analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

.Alkaloids

Composition #2: Gupta, Rajesh., Paarakh, Padmaa M., Gavani, Usha. Pharmacognostical and phytochemical screening of Bauhinia variegata Linn leaves.. Journal of Pharmacy Research, 2009, vol. 2, no. 7, p. 1196–1198. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

methanol and water
Substance:

cardiac glycosides (RF-00010823-PAR)
Analytical method - additional description:

qualitative analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Glycosides Cardiac

Composition #3: Gupta, Rajesh., Paarakh, Padmaa M., Gavani, Usha. Pharmacognostical and phytochemical screening of Bauhinia variegata Linn leaves.. Journal of Pharmacy Research, 2009, vol. 2, no. 7, p. 1196–1198. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

water
Substance:

Saponins (RF-00004333-PAR)
Analytical method - additional description:

qualitative analysis
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Saponins

Composition #4: Gupta, Rajesh., Paarakh, Padmaa M., Gavani, Usha. Pharmacognostical and phytochemical screening of Bauhinia variegata Linn leaves.. Journal of Pharmacy Research, 2009, vol. 2, no. 7, p. 1196–1198. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Substance:

Calcium oxalate (RF-00003960-PAR)
Additional substance description:

crystals
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

oxalates

Composition #5: Di Ciero, L., Oliva, MLV., Torquato, R., Kohler, P., Weder, JKP., Novello, JC., Sampaio, CAM., Oliveira, B., Marangoni, S. The complete amino acid sequence of a trypsin inhibitor from Bauhinia variegata var. candida seeds . journal of protein chemistry, 1998, vol. 17, no. 8, p. 827–834. .

Language:

English (en)
Plant part:

Seed (as part-nature) (A066P)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

%= m M Tris-HCL buffer,pH 8.0
Substance:

Trypsin inhibitors Trypsin inhibitors (RF-00004339-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Trypsin inhibitor

Composition #6: Osuga, IM., Abdulrazak, SA., Ichinohe, T., Fujihara, T. Chemical composition, degradation characteristics and effect of tannin on digestibility of some browse species from Kenya harvested during the wet season . asian-australasian journal of animal sciences, 2005, vol. 18, no. 1, p. 54–60. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

70% aqueous acetone
Substance:

Tannins (RF-00004337-PAR)
Additional substance description:

total extractable tannins
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.6
Internal remarks:

tannins

Composition #7: Sahoo, Deeptanjali., Ahmad, Ateeque., Ahmad, Jamil., Tandon, Sudeep. Chemical Composition of the Essential oil from Flowers of Bauhinia Variegata (Kachnar) of Northern India. JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2013, vol. 16, no. 5, p. 636–640. DOI: 10.1080/0972060X.2013.854503. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydro distillation, Clevenger-type
Substance:

myrcene (RF-00003503-PAR)
Additional substance description:
Analytical method code:

GC-MS (F046A)
Result unit:

Gram/100 gram (G013A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.4
Internal remarks:

myrcene

Composition #8: Sahoo, Deeptanjali., Ahmad, Ateeque., Ahmad, Jamil., Tandon, Sudeep. Chemical Composition of the Essential oil from Flowers of Bauhinia Variegata (Kachnar) of Northern India. JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2013, vol. 16, no. 5, p. 636–640. DOI: 10.1080/0972060X.2013.854503. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Hydro distillation, Clevenger-type
Substance:

Camphor (RF-00003986-PAR)
Additional substance description:

Juniper camphor
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.7
Internal remarks:

Camphor

Endpoint study #1: Kolhe, R., Acharya, R.N., Ashok, B.K., Ravishankar, B. Chronic toxicity study of stem bark powder of Kanchanara (Bauhinia variegata L.) in albino rats. indian journal of natural products and resources, 2014, vol. 5, no. 3, p. 244–248. .

Study relevance:

Human health
Plant part:

Bark (as part-nature) (A066X)
Preparation/Extraction method:

Powder (A06JD)
Type of toxicological test:

subchronic (CHD013TT)
Tested organism:

Rat (as animal) (A0CNV)
Strain of test organism:

Wistar (CHD013ST)
Sex:

Male/Female
Route of exposure:

ORAL: FEED (OECD2230PL)
Exposure duration:

60.0
Unit of exposure duration:

Day (G134A)
Number of organisms dosed:

6
Control groups used:

yes
Endpoint measured:

Dose level (CHD014EP)
Concentration unit:

Milligram/kilogram (G061A)
Effect concentration:

1800
Critical effect:

Other toxicities (TOX19A)
Target tissue:

cardiovascular / haematological: Blood Coagulation (TT010A)
Effect description:

hematological changes (platelets increase)
Effect or parameter linked to the endpoint:

haematology (CHD023BE)
Internal remarks:

hematological changes at high doses