EFSA Compendium of Botanicals

Draft - work in progress

Atherosperma moschatum Labill.

Family:: Atherospermataceae
Approval state:: Approved
Number of articles retrieved:: 76
Number of processed references:: 5

Compositions

#1: Safrole #2: camphor #3: eugenol methyl ether #4: moschatoline (phenolic alkaloid) #5: atheroline (phenolic alkaloid) #6: atherospermidine #7: spermatheridine #8: Atherosperminine #9: 1,8-cineole #10: camphor #11: Safrole #12: Methyleugenol #13: berbamine #14: isocorydine #15: atherospermidine #16: isotetrandrine #17: atherosperminine #18: spermatheridine

Endpoint Studies

Genotoxicity

Composition #1: Scott, Margaret E. The Essential Oil of the Leaves of Atherosperma moschatum ("Australian Sassafras").. Journal of the Chemical Society, Transactions, 1912, vol. 101, p. 1612–3. DOI: 10.1039/ct9120101612. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Steam distillation
Substance:

Safrole (RF-00003651-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Safrole

Composition #2: Scott, Margaret E. The Essential Oil of the Leaves of Atherosperma moschatum ("Australian Sassafras").. Journal of the Chemical Society, Transactions, 1912, vol. 101, p. 1612–3. DOI: 10.1039/ct9120101612. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Steam distillation
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

camphor

Composition #3: Scott, Margaret E. The Essential Oil of the Leaves of Atherosperma moschatum ("Australian Sassafras").. Journal of the Chemical Society, Transactions, 1912, vol. 101, p. 1612–3. DOI: 10.1039/ct9120101612. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Additional extraction description:

Steam distillation
Substance:

methyleugenol (RF-00003931-PAR)
Additional substance description:

eugenol methyl ether
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

eugenol methyl ether

Composition #4: Bick, R. C., Douglas, G. K. Structure of atheroline and moschatoline. I.. Tetrahedron Letters, 1965, no. 51, p. 4655–61. DOI: 10.1016/S0040-4039(01)84030-2. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Additional extraction description:

Unspecified
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

moschatoline
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

UV, IR
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

moschatoline (phenolic alkaloid)

Composition #5: Bick, R. C., Douglas, G. K. Structure of atheroline and moschatoline. I.. Tetrahedron Letters, 1965, no. 51, p. 4655–61. DOI: 10.1016/S0040-4039(01)84030-2. [DOI link]

Language:

English (en)
Plant part:

Bark (as part-nature) (A066X)
Additional extraction description:

Unspecified
Substance:

Alkaloids (RF-00004360-PAR)
Additional substance description:

atheroline
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

atheroline (phenolic alkaloid)

Composition #6: Bick, I.R.C., Douglas, G.K. Yellow constituents of tasmanian sassafras heartwood. Phytochemistry, 1966, vol. 5, no. 1, p. 197–199. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol
Substance:

Atherospermidine (RF-00011233-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

atherospermidine

Composition #7: Bick, I.R.C., Douglas, G.K. Yellow constituents of tasmanian sassafras heartwood. Phytochemistry, 1966, vol. 5, no. 1, p. 197–199. .

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol
Substance:

liriodenine (RF-00003473-PAR)
Additional substance description:

spermatheridine
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

spermatheridine

Composition #8: Bick, I.R.C., Douglas, G.K. Yellow constituents of tasmanian sassafras heartwood. Phytochemistry, 1966, vol. 5, no. 1, p. 197–199. .

Language:

English (en)
Plant part:

Trunk (as part-nature) (A166N)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

MeOH
Substance:

Atherosperminine (RF-00011048-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Atherosperminine

Composition #9: Brophy, Joseph J., Buchanan, Alex M., Copeland, Lachlan M., Dimitriadis, Eugene., Goldsack, Robert J., Hibbert, D. Brynn. Differentiation between the two subspecies of Atherosperma moschatum Labill. (Atherospermataceae) from their leaf oils. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2009, vol. 37, no. 4, p. 479–483. DOI: 10.1016/j.bse.2009.07.007. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.5
Internal remarks:

1,8-cineole

Composition #10: Brophy, Joseph J., Buchanan, Alex M., Copeland, Lachlan M., Dimitriadis, Eugene., Goldsack, Robert J., Hibbert, D. Brynn. Differentiation between the two subspecies of Atherosperma moschatum Labill. (Atherospermataceae) from their leaf oils. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2009, vol. 37, no. 4, p. 479–483. DOI: 10.1016/j.bse.2009.07.007. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.2
Internal remarks:

camphor

Composition #11: Brophy, Joseph J., Buchanan, Alex M., Copeland, Lachlan M., Dimitriadis, Eugene., Goldsack, Robert J., Hibbert, D. Brynn. Differentiation between the two subspecies of Atherosperma moschatum Labill. (Atherospermataceae) from their leaf oils. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2009, vol. 37, no. 4, p. 479–483. DOI: 10.1016/j.bse.2009.07.007. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Safrole (RF-00003651-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

14.8
Internal remarks:

Safrole

Composition #12: Brophy, Joseph J., Buchanan, Alex M., Copeland, Lachlan M., Dimitriadis, Eugene., Goldsack, Robert J., Hibbert, D. Brynn. Differentiation between the two subspecies of Atherosperma moschatum Labill. (Atherospermataceae) from their leaf oils. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2009, vol. 37, no. 4, p. 479–483. DOI: 10.1016/j.bse.2009.07.007. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent Area (G139A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

65.3
Internal remarks:

Methyleugenol

Composition #13: BICK, IRC., CLEZY, PS., CROW, WD. THE ALKALOIDS OF ATHEROSPERMA-MOSCHATUM LABILL .1. ISOLATION OF THE ALKALOIDS AND STRUCTURE OF BERBAMINE. AUSTRALIAN JOURNAL OF CHEMISTRY, 1956, vol. 9, no. 1, p. 111–119. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol, chloroform, petroleum
Substance:

berbamine (RF-00004178-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.6
Internal remarks:

berbamine

Composition #14: BICK, IRC., CLEZY, PS., CROW, WD. THE ALKALOIDS OF ATHEROSPERMA-MOSCHATUM LABILL .1. ISOLATION OF THE ALKALOIDS AND STRUCTURE OF BERBAMINE. AUSTRALIAN JOURNAL OF CHEMISTRY, 1956, vol. 9, no. 1, p. 111–119. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol, chloroform, petroleum
Substance:

isocorydine (RF-00003443-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.007
Internal remarks:

isocorydine

Composition #15: BICK, IRC., CLEZY, PS., CROW, WD. THE ALKALOIDS OF ATHEROSPERMA-MOSCHATUM LABILL .1. ISOLATION OF THE ALKALOIDS AND STRUCTURE OF BERBAMINE. AUSTRALIAN JOURNAL OF CHEMISTRY, 1956, vol. 9, no. 1, p. 111–119. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol, chloroform, petroleum
Substance:

Atherospermidine (RF-00011233-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.006
Internal remarks:

atherospermidine

Composition #16: BICK, IRC., CLEZY, PS., CROW, WD. THE ALKALOIDS OF ATHEROSPERMA-MOSCHATUM LABILL .1. ISOLATION OF THE ALKALOIDS AND STRUCTURE OF BERBAMINE. AUSTRALIAN JOURNAL OF CHEMISTRY, 1956, vol. 9, no. 1, p. 111–119. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol, chloroform, petroleum
Substance:

isotetrandrine (RF-00003452-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.06
Internal remarks:

isotetrandrine

Composition #17: BICK, IRC., CLEZY, PS., CROW, WD. THE ALKALOIDS OF ATHEROSPERMA-MOSCHATUM LABILL .1. ISOLATION OF THE ALKALOIDS AND STRUCTURE OF BERBAMINE. AUSTRALIAN JOURNAL OF CHEMISTRY, 1956, vol. 9, no. 1, p. 111–119. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol, chloroform, petroleum
Substance:

Atherosperminine (RF-00011048-PAR)
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.005
Internal remarks:

atherosperminine

Composition #18: BICK, IRC., CLEZY, PS., CROW, WD. THE ALKALOIDS OF ATHEROSPERMA-MOSCHATUM LABILL .1. ISOLATION OF THE ALKALOIDS AND STRUCTURE OF BERBAMINE. AUSTRALIAN JOURNAL OF CHEMISTRY, 1956, vol. 9, no. 1, p. 111–119. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Methanol, chloroform, petroleum
Substance:

liriodenine (RF-00003473-PAR)
Additional substance description:

spermatheridine
Analytical method code:

Standard Chromatographic tests (paper- thin layer- and column chromatography) (F016A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.002
Internal remarks:

spermatheridine