Draft - work in progress
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- Astragalus mongholicus Bunge
Astragalus mongholicus Bunge
- Family:
- Fabaceae
- Approval state:
- Approved
- Number of articles retrieved:
- 2562
- Number of processed references:
- 4
Composition #1: Lu, Guibao., Lu, Shuhua., Zhang, Guoqing., Xu, Shimei., Li, Deyu., Huang, Qiaoshu. Isolation and identification of flavone-like constituents from Mongolian milkvetch (Astragalus mongholicus). zhongcaoyao, 1984, p. 452–454. .
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Plant part:
Unspecified (A07XD)
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Substance:
calycosin (RF-00004191-PAR)
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
calycosin
Composition #2: Lu, Guibao., Lu, Shuhua., Zhang, Guoqing., Xu, Shimei., Li, Deyu., Huang, Qiaoshu. Isolation and identification of flavone-like constituents from Mongolian milkvetch (Astragalus mongholicus). zhongcaoyao, 1984, p. 452–454. .
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Plant part:
Unspecified (A07XD)
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Substance:
formononetin (RF-00000291-NTR)
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
formononetin
Composition #3: Xie, Wei., Lu, Yili., Yang, Ting., Yan, Shineng., Wei, Liwen., Li, Huiying., Wen, Jiagen., Chen, Guo., Kang, Liqun., Chen, Yuxiang. Determination of 5 bioactive components by TLC and HPLC for quality control of Gankang Granule. zhongguo xiandai yixue zazhi, 2010, p. 2401–2407. .
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Plant part:
Unspecified (A07XD)
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Substance:
Saponins (RF-00004333-PAR)
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Additional substance description:
astragaloside
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
saponin (astragaloside)
Composition #4: Ionkova, I., Kartnig, T. Densitometric determination of cycloartane triterpene saponins from transformed root cultures of Astragalus mongholicus Bge. . pharmazie, 1997, vol. 52, no. 3, p. 218–220. .
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Plant part:
Roots and other underground parts (as part-nature) (A067M)
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Substance:
Saponins (RF-00004333-PAR)
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Additional substance description:
Astragalosides I, II and III
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Analytical method code:
Unspecified (F598A)
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Yes/No Qualitative:
Positive/Present (POS)
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Result type:
Qualitative Value (Binary) (BIN)
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Internal remarks:
Astragalosides I,II and III (saponins)
Genotox #1: YIN, XJ., LIU, DX., WANG, HC., ZHOU, Y. A STUDY ON THE MUTAGENICITY OF 102 RAW PHARMACEUTICALS USED IN CHINESE TRADITIONAL MEDICINE. MUTATION RESEARCH, 1991, vol. 260, no. 1, p. 73–82. .
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Study category:
Mutagenicity
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Type of toxicological test:
bacterial reverse mutation assay (CHD028TT)
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Tested organism:
Salmonella typhimurium (as organism) (A0CPZ)
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Strain of test organism:
TA 98 (CHD029ST)
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Exogenous metabolic activation applied:
with
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Endpoint measured:
gene mutation
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Remarks on genotox study:
positive Ames test TA98 with S9, aqueous extract
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Internal remarks:
Positive Ames test TA98 with S9
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Internal ID:
WOS:A1991FK36700010
Genotox #2: YIN, XJ., LIU, DX., WANG, HC., ZHOU, Y. A STUDY ON THE MUTAGENICITY OF 102 RAW PHARMACEUTICALS USED IN CHINESE TRADITIONAL MEDICINE. MUTATION RESEARCH, 1991, vol. 260, no. 1, p. 73–82. .
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Study category:
Genotoxicity
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Type of toxicological test:
micronucleus assay (CHD051TT)
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Tested organism:
House mouse (as animal) (A0CNT)
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Route of exposure:
OTHER (OECD0PL)
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Exposure duration for in vivo:
1.0
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Unit of exposure duration:
holding (G198A)
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Number of organisms dosed:
60
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Endpoint measured:
DNA damage and/or repair
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Remarks on genotox study:
positive micronucleus study
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Internal remarks:
positive micronucleus study
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Internal ID:
WOS:A1991FK36700010