EFSA Compendium of Botanicals

Draft - work in progress

Asparagus (as plant) // Asparagus officinalis L.

Family:: Asparagaceae
Approval state:: Approved
Number of articles retrieved:: 2673
Number of processed references:: 5

Compositions

#1: saponins (protodioscin and diosgenin) #2: Steroidal saponins #3: Protodioscin (saponin) #4: Protodioscin #5: total saponins

Endpoint Studies

Genotoxicity

Composition #1: Kronabel, D. Antileukemic effectiveness of saponins and sapogenins from Asparagus officinalis L. Antileukämisch wirksame Saponine und Sapogenine aus Asparagus officinalis L . deutsche zeitschrift fur onkologie, 2014, vol. 46, no. 2, p. 62–65. DOI: 10.1055/s-0033-1357646. [DOI link]

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Substance:

steroidal saponins (RF-00010818-PAR)
Additional substance description:

protodioscin and diosgenin
Analytical method code:

Unspecified (F598A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

saponins (protodioscin and diosgenin)

Composition #2: Huang, Xue-Feng., Lin, Yu-Ying., Kong, Ling-Yi. Steroids from the roots of Asparagus officinalis and their cytotoxic activity . journal of integrative plant biology, 2008, vol. 50, no. 6, p. 717–722. DOI: 10.1111/j.1744-7909.2008.00651.x. [DOI link]

Language:

English (en)
Plant part:

Roots and other underground parts (as part-nature) (A067M)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80% ethanol
Substance:

steroidal saponins (RF-00010818-PAR)
Additional substance description:

Asparagoside A, Sarsasapogenin O, and others
Analytical method code:

HPLC with standard detection methods (F019A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Steroidal saponins

Composition #3: Lee, Eun Jin., Yoo, Kil Sun., Patil, Bhimanagouda S. Development of a Rapid HPLC-UV Method for Simultaneous Quantification of Protodioscin and Rutin in White and Green Asparagus Spears . journal of food science, 2010, vol. 75, no. 9, p. C703–C709. DOI: 10.1111/j.1750-3841.2010.01824.x. [DOI link]

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Water, 70% EtOH, 70% MeOH, 70% ACN
Substance:

protodioscin (RF-00004009-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Milligram/gram (G060A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.50-4.83
Internal remarks:

Protodioscin (saponin)

Composition #4: Motoki, Satoru., Kitazawa, Hiroaki., Maeda, Tomoo., Suzuki, Takashi., Chiji, Hideyuki., Nishihara, Eiji., Shinohara, Yutaka. Effects of Various Asparagus Production Methods on Rutin and Protodioscin Contents in Spears and Cladophylls . bioscience biotechnology and biochemistry, 2012, vol. 76, no. 5, p. 1047–1050. DOI: 10.1271/bbb.120143. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

EtOH 70%
Substance:

protodioscin (RF-00004009-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Milligram/gram (G060A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1-21.3
Internal remarks:

Protodioscin

Composition #5: Dou, Fang., Xi, Miaomiao., Wang, Junxian., Tian, Xiangrong., Hong, Liangjian., Tang, Haifeng., Wen, Aidong. alpha-Glucosidase and alpha-amylase inhibitory activities of saponins from traditional Chinese medicines in the treatment of diabetes mellitus . pharmazie, 2013, vol. 68, no. 4, p. 300–304. DOI: 10.1691/ph.2013.2753. [DOI link]

Language:

English (en)
Plant part:

Unspecified (A07XD)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

80 % Ethanol
Substance:

Saponins (RF-00004333-PAR)
Additional substance description:

oleanolic acid equivalents
Analytical method code:

Colorimetry, Spectroscopy (Spectrometry) and Photometry (F008A)
Result unit:

Microgram/gram (G049A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.1604
Internal remarks:

total saponins