EFSA Compendium of Botanicals

Draft - work in progress

Artemisia schmidtiana Maxim.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 12
Number of processed references:: 2

Compositions

#1: verlotorin #2: costunolide #3: reynosin #4: artemorin #5: 1,8-cineole #6: camphor #7: methyleugenol #8: pinocarvone

Endpoint Studies

Genotoxicity

Composition #1: Jakupovic, J., Chau-Thi, T. V., Warning, U., Bohlmann, F., Greger, H. 11β,13-Dihydroguaianolides from Artemisia douglasiana and a thiophene acetylene from A. schmidtiana.. Phytochemistry, 1986, vol. 25, no. 7, p. 1663–7. DOI: 10.1016/S0031-9422(00)81231-5. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

extracted with diethyl ether : petrol (1:1), separated by CC (silica gel), then by TLC
Substance:

Verlotorin (RF-00010898-PAR)
Additional substance description:

sesquiterpenoid lactone
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

HPLC
Result unit:

Milligram (G155A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

8
Internal remarks:

verlotorin

Composition #2: Jakupovic, J., Chau-Thi, T. V., Warning, U., Bohlmann, F., Greger, H. 11β,13-Dihydroguaianolides from Artemisia douglasiana and a thiophene acetylene from A. schmidtiana.. Phytochemistry, 1986, vol. 25, no. 7, p. 1663–7. DOI: 10.1016/S0031-9422(00)81231-5. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

extracted with diethyl ether : petrol (1:1), separated by CC (silica gel), then by TLC
Substance:

costunolide (RF-00003753-PAR)
Additional substance description:

sesquiterpene lactone
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

HPLC
Result unit:

Milligram (G155A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

9
Internal remarks:

costunolide

Composition #3: Jakupovic, J., Chau-Thi, T. V., Warning, U., Bohlmann, F., Greger, H. 11β,13-Dihydroguaianolides from Artemisia douglasiana and a thiophene acetylene from A. schmidtiana.. Phytochemistry, 1986, vol. 25, no. 7, p. 1663–7. DOI: 10.1016/S0031-9422(00)81231-5. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

extracted with diethyl ether : petrol (1:1), separated by CC (silica gel), then by TLC
Substance:

reynosin (RF-00010929-PAR)
Additional substance description:

sesquiterpene lactone
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

HPLC
Result unit:

Milligram (G155A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.5
Internal remarks:

reynosin

Composition #4: Jakupovic, J., Chau-Thi, T. V., Warning, U., Bohlmann, F., Greger, H. 11β,13-Dihydroguaianolides from Artemisia douglasiana and a thiophene acetylene from A. schmidtiana.. Phytochemistry, 1986, vol. 25, no. 7, p. 1663–7. DOI: 10.1016/S0031-9422(00)81231-5. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

extracted with diethyl ether : petrol (1:1), separated by CC (silica gel), then by TLC
Substance:

artemorin (RF-00010930-PAR)
Additional substance description:

sesquiterpene lactone
Analytical method code:

Nuclear Magnetic Resonance (NMR) (F061A)
Analytical method - additional description:

HPLC
Result unit:

Milligram (G155A)
Result expression:

Whole weight (B001A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3
Internal remarks:

artemorin

Composition #5: Radulovic, Niko S., Blagojevic, Polina D. Average mass scan of the total ion chromatograms: A new gas chromatography-mass spectrometry derived variable for fast and reliable multivariate statistical treatment of essential oil compositional data. JOURNAL OF CHROMATOGRAPHY A, 2013, vol. 1301, p. 190–199. DOI: 10.1016/j.chroma.2013.05.039. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.9
Internal remarks:

1,8-cineole

Composition #6: Radulovic, Niko S., Blagojevic, Polina D. Average mass scan of the total ion chromatograms: A new gas chromatography-mass spectrometry derived variable for fast and reliable multivariate statistical treatment of essential oil compositional data. JOURNAL OF CHROMATOGRAPHY A, 2013, vol. 1301, p. 190–199. DOI: 10.1016/j.chroma.2013.05.039. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

6.8
Internal remarks:

camphor

Composition #7: Radulovic, Niko S., Blagojevic, Polina D. Average mass scan of the total ion chromatograms: A new gas chromatography-mass spectrometry derived variable for fast and reliable multivariate statistical treatment of essential oil compositional data. JOURNAL OF CHROMATOGRAPHY A, 2013, vol. 1301, p. 190–199. DOI: 10.1016/j.chroma.2013.05.039. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

methyleugenol (RF-00003931-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.6
Internal remarks:

methyleugenol

Composition #8: Radulovic, Niko S., Blagojevic, Polina D. Average mass scan of the total ion chromatograms: A new gas chromatography-mass spectrometry derived variable for fast and reliable multivariate statistical treatment of essential oil compositional data. JOURNAL OF CHROMATOGRAPHY A, 2013, vol. 1301, p. 190–199. DOI: 10.1016/j.chroma.2013.05.039. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

pinocarvone (RF-00003547-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.1
Internal remarks:

pinocarvone