EFSA Compendium of Botanicals

Draft - work in progress

Artemisia campestris L.

Family:: Asteraceae
Approval state:: Approved
Number of articles retrieved:: 251
Number of processed references:: 11

Compositions

#1: 1,8-cineole #2: Artemisinin (sesquiterpene lactone) #3: 1,8-cineole #4: Camphor #5: Camphor #6: Artmisinin (sequterpene lactone) in leaves #7: Artemisinin (sesquiterpene lactone) in buds #8: Artemisinin (sesquiterpene lactone) in flowers #9: Myrcene #10: Myrcene #11: Myrcene #12: dihydrocarvone #13: 1,8-cineole #14: cedrol #15: Myrcene #16: Humulene epoxide #17: Condensed tannins

Endpoint Studies

Genotoxicity

Composition #1: Guven, Kasim Cemal. Turkish Artemisia species. II. Artemisia campestris.. folia pharmaceutica (istanbul), 1963, vol. 5, p. 586–91. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

7.8
Internal remarks:

1,8-cineole

Composition #2: Erdemoglu, Nurgun., Orhan, Ilkay., Kartal, Murat., Adiguzel, Nezaket., Bani, Baris. Determination of artemisinin in selected Artemisia L. species of Turkey by reversed phase HPLC.. records of natural products, 2007, vol. 1, no. 2-3, p. 36–43. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

n-hexane
Substance:

artemisinin (RF-00003658-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Yes/No Qualitative:

Positive/Present (POS)
Result type:

Qualitative Value (Binary) (BIN)
Internal remarks:

Artemisinin (sesquiterpene lactone)

Composition #3: Mucciarelli, M., Caramiello, R., Maffei, M., Chialva, P. Essential oils from some Artemisia species growing spontaneously in north-west Italy. flavour and fragrance journal, 1995, vol. 10, no. 1, p. 25–32. DOI: 10.1002/ffj.2730100105. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

19.2
Internal remarks:

1,8-cineole

Composition #4: Mucciarelli, M., Caramiello, R., Maffei, M., Chialva, P. Essential oils from some Artemisia species growing spontaneously in north-west Italy. flavour and fragrance journal, 1995, vol. 10, no. 1, p. 25–32. DOI: 10.1002/ffj.2730100105. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.7
Internal remarks:

Camphor

Composition #5: Belhattab, R., Boudjouref, M., Barroso, J.G., Pedro, L.P., Figueirido, A.C. Essential oil composition from Artemisia campestris grown in Algeria. advances in environmental biology, 2011, vol. 5, no. 2 SPEC. ISSUE, p. 429–432. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Camphor (RF-00003986-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

9.2
Internal remarks:

Camphor

Composition #6: Ranjbar, M., Naghavi, M.R., Alizadeh, H., Soltanloo, H. Expression of artemisinin biosynthesis genes in eight Artemisia species at three developmental stages. industrial crops and products, 2015, vol. 76, p. 836–843. DOI: 10.1016/j.indcrop.2015.07.077. [DOI link]

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether
Substance:

artemisinin (RF-00003658-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Milligram/gram (G060A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.4
Internal remarks:

Artmisinin (sequterpene lactone) in leaves

Composition #7: Ranjbar, M., Naghavi, M.R., Alizadeh, H., Soltanloo, H. Expression of artemisinin biosynthesis genes in eight Artemisia species at three developmental stages. industrial crops and products, 2015, vol. 76, p. 836–843. DOI: 10.1016/j.indcrop.2015.07.077. [DOI link]

Language:

English (en)
Plant part:

Bud (as part-nature) (A066Z)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

Petroleum ether
Substance:

artemisinin (RF-00003658-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Milligram/gram (G060A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.9
Internal remarks:

Artemisinin (sesquiterpene lactone) in buds

Composition #8: Ranjbar, M., Naghavi, M.R., Alizadeh, H., Soltanloo, H. Expression of artemisinin biosynthesis genes in eight Artemisia species at three developmental stages. industrial crops and products, 2015, vol. 76, p. 836–843. DOI: 10.1016/j.indcrop.2015.07.077. [DOI link]

Language:

English (en)
Plant part:

Flower (as part-nature) (A067B)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

petroleum ether
Substance:

artemisinin (RF-00003658-PAR)
Analytical method code:

High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) (F018A)
Result unit:

Milligram/gram (G060A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

0.8
Internal remarks:

Artemisinin (sesquiterpene lactone) in flowers

Composition #9: Silva, AMS., Seca, AML., Vasconcelos, JMJ., Cavaleiro, JAS., Silvestre, AJD., Domingues, FMJ., Neto, CP., Rauter, AP., Palma, FB., Justino, J., Araujo, ME., PinaDosSantos, S. Chemical composition of Artemisia campestris and Hibiscus cannabinus. natural products in the new millennium: prospects and industrial application, 2002, vol. 47, p. 47–57. .

Language:

English (en)
Plant part:

Live plants (as part-nature) (A0BA0)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

Unspecified (F598A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.0
Internal remarks:

Myrcene

Composition #10: Akrout, A., Chemli, R., Simmonds, M., Kite, G., Hammami, M., Chreif, I. Seasonal variation of the essential oil of Artemisia campestris L.. journal of essential oil research, 2003, vol. 15, no. 5, p. 333–336. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myrcene (RF-00003503-PAR)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

1.2-4.3
Internal remarks:

Myrcene

Composition #11: Dob, T., Dahmane, D., Berramdane, T., Chelghoum, C. Chemical composition of the essential oil of Artemisia campestris L. from Algeria . pharmaceutical biology, 2005, vol. 43, no. 6, p. 512–514. DOI: 10.1080/13880200500220664. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

3.3
Internal remarks:

Myrcene

Composition #12: Dob, T., Dahmane, D., Berramdane, T., Chelghoum, C. Chemical composition of the essential oil of Artemisia campestris L. from Algeria . pharmaceutical biology, 2005, vol. 43, no. 6, p. 512–514. DOI: 10.1080/13880200500220664. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

Dihydrocarvone (RF-00011286-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.9
Internal remarks:

dihydrocarvone

Composition #13: Dob, T., Dahmane, D., Berramdane, T., Chelghoum, C. Chemical composition of the essential oil of Artemisia campestris L. from Algeria . pharmaceutical biology, 2005, vol. 43, no. 6, p. 512–514. DOI: 10.1080/13880200500220664. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

1,8-cineole (RF-00003470-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

2.6
Internal remarks:

1,8-cineole

Composition #14: Dob, T., Dahmane, D., Berramdane, T., Chelghoum, C. Chemical composition of the essential oil of Artemisia campestris L. from Algeria . pharmaceutical biology, 2005, vol. 43, no. 6, p. 512–514. DOI: 10.1080/13880200500220664. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

alpha-cedrol (RF-00003645-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

5.4
Internal remarks:

cedrol

Composition #15: Aicha, Neffati., Ines, Skandrani., Mohamed, Ben Sghaier., Ines, Bouhlel., Soumaya, Kilani., Kamel, Ghedira., Mohamed, Neffati., Imed, Chraief., Mohamed, Hammami., Leila, Chekir-Ghedira. Chemical composition, mutagenic and antimutagenic activities of essential oils from (Tunisian) Artemisia campestris and Artemisia herba-alba . journal of essential oil research, 2008, vol. 20, no. 5, p. 471–477. .

Language:

English (en)
Plant part:

Leaves (as part-nature) (A0EKT)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

myrcene (RF-00003503-PAR)
Analytical method code:

GC-MS (F046A)
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

4.1
Internal remarks:

Myrcene

Composition #16: Judzentiene, Asta., Budiene, Jurga., Butkiene, Rita., Kupcinskiene, Eugenija., Laffont-Schwob, Isabelle., Masotti, Veronique. Caryophyllene Oxide-rich Essential Oils of Lithuanian Artemisia campestris ssp. campestris and Their Toxicity . natural product communications, 2010, vol. 5, no. 12, p. 1981–1984. .

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Essential oil (as part-nature) (A166Q)
Substance:

epoxides (RF-00010829-PAR)
Additional substance description:

humulene epoxide
Result unit:

Percent (G138A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

<=8.1
Internal remarks:

Humulene epoxide

Composition #17: Boufennara, S., Lopez, S., Bousseboua, H., Bodas, R., Bouazza, L. Chemical composition and digestibility of some browse plant species collected from Algerian arid rangelands . spanish journal of agricultural research, 2012, vol. 10, no. 1, p. 88–98. DOI: 10.5424/sjar/2012101-134-11. [DOI link]

Language:

English (en)
Plant part:

Aerial part of plants (as part-nature) (A166F)
Extraction/Preparation method:

Solvent extraction (A0BZR)
Additional extraction description:

unspecified
Substance:

Proanthocyanidins (condensed tannins) Proanthocyanidins (condensed tannins) (RF-00004370-PAR)
Analytical method code:

Unspecified (F598A)
Result unit:

Gram/kilogram (G015A)
Result expression:

Dry matter (B002A)
Result type:

Numerical Value (VAL)
Value (concentration, content):

114.3
Internal remarks:

Condensed tannins